The aim of this study was to verify quantitatively and qualitatively the prevalence of the manifestations of extrapyramidal side-effects in a sample of Egyptian schizophrenic patients treated with oral doses of neuroleptics. Fifty-five schizophrenic patients according to ICD-18 taking oral phenothiazines were observed for the appearance of EPS. 36.4% of the cases developed EPS with moderate doses of oral phenothiazines. 60% of schizophrenic patients are receiving anti-parkinsonian drugs unnecessarily and the risk of return of EPS after discontinuation of anti-parkinsonian drugs is small (30%).